发明名称 |
DENATURAT STABLE AND/OR PROTEASE RESISTANT, CHAPERONE-LIKE OLIGOMERIC PROTEINS, POLYNUCLEOTIDES ENCODING SAME AND THEIR USES |
摘要 |
Novel denaturant-stable, protease resistant, homo-oligomeric proteins, also referred to herein as stable proteins (SPs), having chaperone-like activity; methods of production and purification of SPs; nucleic acids encoding SPs; methods of isolating nucleic acids encoding SPs; antibodies recognizing SPs; the use of SPs for stabilizing, refolding, repairing, preventing aggregation and de-aggregating macromolecules such as proteins; fusion proteins including SPs; nucleic acid constructs encoding the fusion proteins; and their uses in a variety of methods and applications. |
申请公布号 |
WO02070647(A3) |
申请公布日期 |
2004.10.07 |
申请号 |
WO2002IL00174 |
申请日期 |
2002.03.05 |
申请人 |
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW;WANG, WANGXIA;PELAH, DAN;ALEGRAND, TAL;SHOSEYOV, ODED;ALTMAN, ARIE |
发明人 |
WANG, WANGXIA;PELAH, DAN;ALEGRAND, TAL;SHOSEYOV, ODED;ALTMAN, ARIE |
分类号 |
A61K38/00;C07K14/415;C12N9/96;C12N15/29;C12N15/82 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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