| 发明名称 |
USE OF P97 AS AN ENZYME DELIVERY SYSTEM FOR THE DELIVERY OF THERAPEUTIC LYSOSOMAL ENZYMES |
| 摘要 |
The present invention provides for compositions and methods for treating, ameliorating or preventing a lysosomal storage disease by administering to a patient suffering from a lysosomal storage disease a P97 conjugated with an enzyme which is capable of transportation into the lysosomes of cells on either sides of the blood brain barrier. |
| 申请公布号 |
EP1463512(A2) |
申请公布日期 |
2004.10.06 |
| 申请号 |
EP20030717870 |
申请日期 |
2003.01.10 |
| 申请人 |
BIOMARIN PHARMACEUTICAL, INC. |
发明人 |
STARR, CHRISTOPHER, M.;ZANKEL, TODD |
| 分类号 |
A61K38/17;A61K38/44;A61K47/48;C12P21/04;G01N33/50;G01N33/566;(IPC1-7):A61K31/70;A61K38/46;A61K39/395;C07K1/00;C12P21/06;G01N33/53 |
主分类号 |
A61K38/17 |
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