发明名称 |
Chimeric fibroblast growth factor proteins, nucleic acid molecules, and uses thereof |
摘要 |
A chimeric fibroblast growth factor protein and recombinant nucleic acid molecule encoding the same are disclosed. The chimeric fibroblast growth factor protein is characterized by: fibroblast growth factor biological activity in the absence of heparan sulfate and, entry into a living cell in the absence of a receptor that binds to FGF. Also disclosed are a method of making the chimeric fibroblast growth factor protein and methods of using the chimeric fibroblast growth factor protein to promote fibroblast growth factor activity in a cell and to enhance a biological process associated with fibroblast growth factor activity.
|
申请公布号 |
US6800286(B1) |
申请公布日期 |
2004.10.05 |
申请号 |
US19990377675 |
申请日期 |
1999.08.19 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF COLORADO |
发明人 |
OLWIN BRADLEY B.;ROSENTHAL RICHARD SCOTT |
分类号 |
A61K38/00;C07K14/50;C07K16/22;(IPC1-7):A61K39/00;A61K38/18;A61K38/24;C07K1/00 |
主分类号 |
A61K38/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|