发明名称 |
Method of monitoring a biological system by labeling with an apo metal binding protein |
摘要 |
The present invention is directed to reporter molecules and tags that may be used to monitor a target substance in a biological system. More particularly, the present invention relates to the use of an apo metal binding protein as a reporter molecule or tag. An apo metal binding protein may be bound to a protein or tissue or introduced into a cell. The invention also relates to methods of utilizing the apo metal binding protein for detecting a cell expressing a protein of interest, localizing a protein in a cell, and designing a therapeutic agent for treating a disease or infection.
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申请公布号 |
US6800437(B1) |
申请公布日期 |
2004.10.05 |
申请号 |
US20000633232 |
申请日期 |
2000.08.04 |
申请人 |
TIBOTEC BVBA |
发明人 |
DIERYNCK INGE;ROELANT CHRISTIAAN HUBERT SIMON;PAUWELS RUDI WILFRIED JAN;VAN ACKER KOENRAAD LODEWIJK AUGUST;DE KERPEL JAN OCTAAF ANTOON |
分类号 |
G01N33/50;G01N33/58;(IPC1-7):C12Q1/68 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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