发明名称 |
Manganese superoxide dismutase regulatory elements and uses thereof |
摘要 |
A novel transcriptional regulatory element which was isolated from the MnSOD gene and which exhibits promoter-enhancer activity is disclosed. The promoter-enhancer activity of the element is further modulated by inflammatory mediators to regulate transcription. Methods of using the promoter-enhancer element to regulate gene expression, and therapeutic uses involving the promoter-enhancer element are also described.
|
申请公布号 |
US6800458(B1) |
申请公布日期 |
2004.10.05 |
申请号 |
US20010856766 |
申请日期 |
2001.08.28 |
申请人 |
UNIVERSITY OF FLORIDA |
发明人 |
NICK HARRY S.;ROGERS RICHARD;VALENTINE JOHN F. |
分类号 |
A61K48/00;C07K14/47;C12N9/02;(IPC1-7):C12N15/00;C12N15/09;C12N15/86;C07H21/04;C12P21/06 |
主分类号 |
A61K48/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|