发明名称 Method and apparatus for high-throughput biological-activity screening of cells and/or compounds
摘要 First entities consisting in cells or microorganisms (BIO) and second entities consisting in compounds or compound units, carried typically by microbeads (BEAD), are trapped selectively within closed movable potential cages (S1) by means of dielectrophoretic force generated by mutually opposed electrodes (M1, M2). The cages are set in relative motion so as to bring about the interaction of selected first and second entities, causing the cages containing them to fuse, whereupon results are obtained preferably by reinstating the original cages and/or observing previously empty adjacent cages. The procedure takes place in a device (DE) with two separate chambers (F, FL) connected one to the other by way of a narrow passage (D) and finished with respective selectively controllable inlets and outlets (I1, I2; O1, O2) through which a liquid or semi-liquid buffer (L) can be pumped in or out.
申请公布号 US2004191789(A1) 申请公布日期 2004.09.30
申请号 US20040476467 申请日期 2004.05.03
申请人 MANARESI NICOLO;MEDORO GIANNI;ALTOMARE LUIGI;TARTAGNI MARCO;GUERRIERI ROBERTO 发明人 MANARESI NICOLO;MEDORO GIANNI;ALTOMARE LUIGI;TARTAGNI MARCO;GUERRIERI ROBERTO
分类号 G01N33/543;G01N33/561;(IPC1-7):C12Q1/68 主分类号 G01N33/543
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