Compounds that may be used to inhibit histone deacetylase having the formula (I) or formula (II) wherein M is a substituent capable of complexing with a deacetylase catalytic site and/or a metal ion; L is a substituent providing between 0-10 atoms separation between the M substituent and the remainder of the compound; and Z and Q are as defined herein.
申请公布号
CA2518318(A1)
申请公布日期
2004.09.30
申请号
CA20042518318
申请日期
2004.03.17
申请人
TAKEDA SAN DIEGO, INC.
发明人
CAO, SHELDON X.;BROWN, JASON W.;GANGLOFF, ANTHONY R.;JENNINGS, ANDREW J.;BRESSI, JEROME C.;XIAO, XIAO-YI;STAFFORD, JEFFREY A.;VU, PHONG H.