This invention relates to peptidyl compounds of the formulas (I) and (II) active as cathepsin S, a cysteine protease, inhibitors. The compounds are selective, reversible inhibitors of the cathepsin S are therefore useful in the treatment of autoimmune and other diseases. The invention also relates t o processes for preparing such compounds and pharmaceutical compositions comprising them.
申请公布号
CA2518728(A1)
申请公布日期
2004.09.30
申请号
CA20042518728
申请日期
2004.03.03
申请人
BOEHRINGER INGELHEIM PHARMACEUTICALS, INC.
发明人
YOUNG, ERICK RICHARD ROUSH;WARD, YANCEY DAVID;SUN, SANXING;LIU, WEIMIN;HICKEY, EUGENE R.