发明名称 |
Insulin producing cells derived from human embryonic stem cells |
摘要 |
The present invention discloses insulin producing cells derived from human embryonic stem cells. Methods of generating, enriching, selecting, cloning and isolating populations of insulin-producing embryonic cell lines are disclosed. Insulin production in these cells can be glucose responsive or otherwise regulatable. Advantageously, these insulin producing cells can be stable cell lines derived from stable transfectants of hESC. Methods of using these cells, cell populations or cell lines particularly for cell replacement therapy are also disclosed. |
申请公布号 |
US2004191901(A1) |
申请公布日期 |
2004.09.30 |
申请号 |
US20030714348 |
申请日期 |
2003.11.14 |
申请人 |
ASSADY SUHEIR;MAOR GILA;AMIT MICHAL;ITSKOVITZ-ELDOR JOSEPH;SKORECKI KARL L.;TZUKERMAN MATY |
发明人 |
ASSADY SUHEIR;MAOR GILA;AMIT MICHAL;ITSKOVITZ-ELDOR JOSEPH;SKORECKI KARL L.;TZUKERMAN MATY |
分类号 |
C12N15/09;A61K35/12;A61K35/48;A61P1/18;A61P3/10;C12N5/02;C12N5/071;C12N5/10;(IPC1-7):C12N5/08 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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