DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH DOPAMINE RECEPTOR D1A (DRD1)

摘要

The invention provides a human DRD1 which is associated with the cardiovascular disorders, gastrointestinal and liver diseases, inflammatory diseases, hematological disorders, neurological disorders, respiratory diseases and urological disorders. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular disorders, gastrointestinal and liver diseases, inflammatory diseases, hematological disorders, neurological disorders, respiratory diseases and urological disorders. The invention also features compounds which bind to and/or activate or inhibit the activity of DRD1 as well as pharmaceutical compositions comprising such compounds.