MODULATORS OF THE NOTCH SIGNALING PATHWAY IMMOBILIZED ON PARTICLES FOR MODIFYING IMMUNE RESPONSES

摘要

The invention provides a particle capable of being inserted into or taken up by a cell comprising i ) a polynucleotide coding for a modulator of Notch signalling; and ii) a polynucleotide coding for an antigen or antigenic determinant thereof. Methods for using the particles are also described.