The invention provides methods for identifying a modulator of quorum sensing signaling in bacteria, and for identifying a quorum sensing controlled gene in bacteria. In addition, the invention provides quorum sensing controlled genetic loci in Pseudomas aeruginosa. Novel indicator strains and vectors for engineering the strains for use in the method of the invention are also provided.
申请公布号
WO2004083385(A2)
申请公布日期
2004.09.30
申请号
WO2004US07467
申请日期
2004.03.11
申请人
UNIVERSITY OF IOWA RESEARCH FOUNDATION;GREENBERG, EVERETT, P.;SCHUSTER, MARTIN;LOSTROH, CANDI