发明名称 |
Tissue-specific transporter inhibitor |
摘要 |
The present invention is to provide a tissue-specific transporter inhibitor which is not absorbed through the digestive tract and can prevent deterioration in the QOL of a patient caused by diet therapy, and a therapeutic drug for tissue dysfunction diseases and a therapeutic drug for suppressing the progress of chronic renal failure containing the inhibitor as an active ingredient. A tissue-specific transporter inhibitor which is not absorbed through the digestive tract is constructed by introducing a dipeptide which is a ligand of an oligopeptide transporter 1 into a supramolecular structure polyrotaxane wherein its structurally modified active residue is expected to be excellent in the interaction with a transmembrane transporter.
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申请公布号 |
US2004191211(A1) |
申请公布日期 |
2004.09.30 |
申请号 |
US20030742335 |
申请日期 |
2003.12.19 |
申请人 |
TSUJI AKIRA;TAMAI IKUMI;SAI YOSHIMICHI;YUI NOUBUHIKO;OYA TORU;MIYAMOTO KEN-ICHI |
发明人 |
TSUJI AKIRA;TAMAI IKUMI;SAI YOSHIMICHI;YUI NOUBUHIKO;OYA TORU;MIYAMOTO KEN-ICHI |
分类号 |
A61K31/724;A61K31/765;A61K31/77;A61K38/05;A61K45/00;A61K47/48;A61P1/00;A61P13/12;A61P43/00;(IPC1-7):A61K31/785 |
主分类号 |
A61K31/724 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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