A METHOD FOR OBTAINING STRUCTURAL INFORMATION ABOUT AN ENCODED MOLECULE

摘要

Disclosed is a method for obtaining structural information about an encoded molecule, wherein the encoded molecule has been produced by a process comprising reacting a plurality of chemical entities, said chemical entities being coded for by codons on a nucleic acid template. The method comprises the steps of providing an array comprising a plurality of single stranded nucleic acid probes immobilized in discrete areas of a solid support, wherein the nucleic acid probes are capable of hybridising to a codon of the template, adding the nucleic acid template or a sequence complementary thereto, to the array under conditions which allow for hybridisation, and observing the discrete areas of the support in which an hybridisation event has occurred.