| 发明名称 |
SUBSTITUTED PIPERIDINE AND PIPERAZINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS |
| 摘要 |
<p>The present invention relates to novel substituted piperidine and piperazine derivatives as melanocortin-4 receptor (MC-4R) modulators. MC-4R agonists of the invention can be used for the treatment of disorders and diseases such as obesity, diabetes, and sexual dysfunction, whereas the MC-4R antagonists are useful for the treatment of disorders and diseases such as cancer cachexia, muscle wasting, anorexia, anxiety and depression. All diseases and disorders where the regulation of the MC-4R is involved can be treated with the compounds of the invention.</p> |
| 申请公布号 |
WO2004083199(A1) |
申请公布日期 |
2004.09.30 |
| 申请号 |
WO2004EP02908 |
申请日期 |
2004.03.19 |
| 申请人 |
MYOCONTRACT LTD.;SOEBERDT, MICHAEL;WEYERMANN, PHILIPP;VON SPRECHER, ANDREAS |
发明人 |
SOEBERDT, MICHAEL;WEYERMANN, PHILIPP;VON SPRECHER, ANDREAS |
| 分类号 |
A61K31/451;A61K31/4709;A61K31/4725;A61K31/497;A61P3/04;A61P15/00;A61P25/22;A61P25/24;C07D401/12;C07D405/12;(IPC1-7):C07D401/12;A61K31/470;A61K31/472 |
主分类号 |
A61K31/451 |
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