Method for producing a vaccine

摘要

There is disclosed a method of producing an autologous-antibody-containing vaccine, which method is characterized by the following steps: providing an antibody-containing fluid from an autologous-antibody-containing body fluid or from autologous cell or tissue preparations, treating the antibody-containing fluid with a solid carrier on which ligands have been immobilized which bond to a certain group of antibodies, with the proviso that, as said ligands, no antibodies or their fragments with the same idiotype are used which are directed against tumor-associated antigens, recovering the antibodies which bond to the ligands, and working up the recovered antibodies to an autologous vaccine which comprises an efficient amount of a few micrograms to up to one gram of antibodies.