| 发明名称 |
ANTI-CD45RB ANTIBODIES FOR USE IN TREATING AUTOIMMUNE DISEASE AND TRANSPLANT REJECTION |
| 摘要 |
Antibodies which specifically recognize the human CD45 isoform RB are presented. These antibodies may be used to block undesirable immune reactions in patients with transplant rejection and autoimmune diseases such as rheumatoid arthritis, multiple sclerosis and autoimmune diabetes. Preferred antibodies are fully human, monoclonal antibodies. |
| 申请公布号 |
EP1461081(A2) |
申请公布日期 |
2004.09.29 |
| 申请号 |
EP20020786850 |
申请日期 |
2002.12.02 |
| 申请人 |
ABGENIX, INC. |
发明人 |
FOLTZ, IAN;BABCOOK, JOHN;PALATHUMPAT, VARGHESE;YANG, XIAO-DONG;KING, CHADWICK, T. |
| 分类号 |
A61K39/395;C12N15/09;A61P37/00;A61P37/02;A61P37/06;A61P43/00;C07K16/28;C07K16/40;C07K16/46;C12N15/13;C12P21/08;(IPC1-7):A61K39/395 |
主分类号 |
A61K39/395 |
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