发明名称 Compounds that reversibly bind bicarbonate
摘要 The invention relates to a compound having the general formula I <CHEM> wherein A1 and A2 are selected from the group consisting of carbon (=CH-) and nitrogen (=N-); D1 and D2 are selected from the group consisting of-OH, -SH and -NHR<1> groups, wherein R<1> is hydrogen, hydrophilic substituent, hydrophobic substituent or linker; X1 and X2 are selected from the group consisting of oxygen (=O), sulphur (=S) and =NR<2> group, wherein R<2> is hydrogen, hydrophilic substituent, hydrophobic substituent or linker; X3 is selected from the group consisting of oxygen (=O), sulphur (=S), =NR<2> group and two singly bonded moieties, wherein both moieties are hydrogen or one moiety is hydrogen and the other moiety is selected from the group of hydrophilic substituent, hydrophobic substituent and linker; and R1-R9 are selected from the group consisting of hydrogen, electron donating substituent, electron accepting substituent, hydrophilic substituent, hydrophobic substituent and linker, or R3 and R4 and/or R6 and R7 form together an aromatic or heteroaromatic, substituted or unsubstituted ring and the remaining moieties R1-R9 are as defined above. <IMAGE>
申请公布号 EP1462452(A1) 申请公布日期 2004.09.29
申请号 EP20040006339 申请日期 2004.03.17
申请人 ROCHE DIAGNOSTICS GMBH;F. HOFFMANN-LA ROCHE AG 发明人 BELL, THOMAS W.;CHEN, JINHUA;KHASANOV, ALISHER B.
分类号 C07D471/22;(IPC1-7):C07D471/22;G01N21/00;C07D471/04;C07D471/14 主分类号 C07D471/22
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