Process for preparing 9-(2-(diethylphosphonomethoxy)ethyl)-adenine
摘要
The present invention relates to a method for preparing adefovir dipivoxil comprising contacting 9-Ä2-(phosphonomethoxy)ethylÜadenine with chloromethyl pivalate in 1-methyl-2-pyrrolidinone and a trialkylamine and recovering adefovir dipivoxil.
申请公布号
EP1256585(B1)
申请公布日期
2004.09.29
申请号
EP20020016429
申请日期
1998.07.23
申请人
GILEAD SCIENCES, INC.
发明人
ARIMILLI, MURTY N;LEE, THOMAS, T.K;MANES, LAWRENCE V;MUNGER, JOHN D.,JR;PRISBE, ERNEST J;SCHULTZE, LISA, M;KELLY, DAPHNE E
