摘要 |
A nitrogen-containing six-membered heterocyclic compound having substituents -X-A-R<3>, -N(R<1>)-(Ph substituted by R<2>), and -CONH2, a salt thereof, a prodrug thereof, and a Syk inhibitor containing the same as an active ingredient. (In the formula, A: a (substituted) lower alkylene, a (substituted) arylene, or the like; X: NR<4>, CONR<4>, NR<4>CO, O, or S; R<1>, R<4>: H, a lower alkyl, -CO-lower alkyl, or -SO2-lower alkyl; R<2>: H, a (substituted) lower alkyl, -O-lower alkyl, -S-lower alkyl, -O-aryl, nitro, cyano, or the like; R<3>: -CO2H, -CO2-lower alkyl, -lower alkylene-CO2H, -NH2, -alkylene-NH2 or the like.
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