发明名称 Heterocyclecarboxamide derivative
摘要 A nitrogen-containing six-membered heterocyclic compound having substituents -X-A-R<3>, -N(R<1>)-(Ph substituted by R<2>), and -CONH2, a salt thereof, a prodrug thereof, and a Syk inhibitor containing the same as an active ingredient. (In the formula, A: a (substituted) lower alkylene, a (substituted) arylene, or the like; X: NR<4>, CONR<4>, NR<4>CO, O, or S; R<1>, R<4>: H, a lower alkyl, -CO-lower alkyl, or -SO2-lower alkyl; R<2>: H, a (substituted) lower alkyl, -O-lower alkyl, -S-lower alkyl, -O-aryl, nitro, cyano, or the like; R<3>: -CO2H, -CO2-lower alkyl, -lower alkylene-CO2H, -NH2, -alkylene-NH2 or the like.
申请公布号 US6797706(B1) 申请公布日期 2004.09.28
申请号 US20010009276 申请日期 2001.12.10
申请人 YAMANOUCHI PHARMACEUTICAL CO., LTD. 发明人 HISAMICHI HIROYUKI;KAWAZOE SOUICHIROU;TANABE KAZUHITO;ICHIKAWA ATSUSHI;ORITA AKIKO;SUZUKI TAKAYUKI;ONDA KENICHI;TAKEUCHI MAKOTO
分类号 A61P29/00;A61P37/08;A61P43/00;C07D213/82;C07D239/48;C07D241/26;C07D253/07;(IPC1-7):A61K31/33;A61K31/496;C07D241/00;C07D241/02 主分类号 A61P29/00
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