| 摘要 |
FIELD: virology, pharmaceutical industry, pharmacy. ^ SUBSTANCE: invention relates to the development of agent for inhibition of reproduction of enveloped viruses. Invention proposes the group of inventions combined by the general inventive project involving a method for preparing compounds, development of pharmaceutical compositions and methods for treatment using their, agent based on fullerene polycarboxylic anions for inhibition of activity of enveloped viruses in treatment of diseases caused by these viruses. Choice of such quantitative ratios of components and conditions for carrying out the reaction provide preparing products of poly-addition. In carrying out synthesis amount of amino acid has to exceed amount of fullerene by more 50 times. Invention relates also to a method for inhibition of reproduction of enveloped viruses in treatment of diseases caused by HIV/AIDS, herpes infections, viral hepatitis C. Invention provides preparing product that has unlimited solubility in water, necessary bioavailability, high effectiveness of effect on infected cells and low toxicity. The content of basic substance in the end product is 87%, not less. Process shows technological effectiveness and can be used in pharmaceutical industry. ^ EFFECT: improved preparing method, improved inhibiting method, valuable medicinal properties of agent. ^ 5 cl |
