发明名称 |
(-)-5-(3-Chlorophenyl)-ec-(4-chlorophenyl)-oc-(1-methyl-lH-imidazol-5-yl)- tetrazolo [1,5-a] quinazoline-7-methanamine a farnesyl transferase inhibiting 1,2-annelated quinoline enantiomer |
摘要 |
Disclosed herein is a farnesyl transferase inhibiting 1,2-annelated quinoline enantiomer such as (-)-5-(3-Chlorophenyl)-a-(4-chlorophenyl)-a-(1-methyl-1H-imidazol-5-yl)tetrazolo-[1,5-a]quinazoline-7-methanamine and its pharmaceutically acceptable acid addition salts, and the use of such compounds in medicine especially for the treatment of cancer. |
申请公布号 |
NZ522481(A) |
申请公布日期 |
2004.09.24 |
申请号 |
NZ20010522481 |
申请日期 |
2001.06.13 |
申请人 |
JANSSEN PHARMACEUTICA N |
发明人 |
VENET, MARC GASTON;ANGIBAUD, PATRICK RENE;END, DAVID WILLIAM |
分类号 |
A61K31/519;A61P35/00;C07D487/04;(IPC1-7):C07D487/04 |
主分类号 |
A61K31/519 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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