| 发明名称 |
Construction of Pasteurella haemolytica vaccines |
| 摘要 |
Methylation of DNA can be a critical step in the introduction of DNA into P. haemolytica. A methyltransferase has been isolated and molecularly cloned for this purpose. Use of the methyltransferase has allowed construction of defined, attenuated mutants for use as vaccines to protect cattle.
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| 申请公布号 |
US6793927(B1) |
申请公布日期 |
2004.09.21 |
| 申请号 |
US19980210747 |
申请日期 |
1998.12.15 |
| 申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF AGRICULTURE;BIOTECHNOLOGY RESEARCH AND DEVELOPMENT CORPORATION |
发明人 |
BRIGGS ROBERT E.;TATUM FRED M. |
| 分类号 |
A61K39/102;C12N9/10;C12N9/22;C12N15/10;C12N15/74;(IPC1-7):A61K39/102 |
主分类号 |
A61K39/102 |
| 代理机构 |
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