摘要 |
This invention discloses novel gamma secretase inhibitors of the formula: wherein: R<SUP>1 </SUP>is a substituted aryl or substituted heteroaryl group; R<SUP>2 </SUP>is an R<SUP>1 </SUP>group, alkyl, -X(CO)Y, or alkylene-X(CO)Y wherein X and Y are as defined herein; each R<SUP>3 </SUP>and each R<SUP>3A </SUP>are independently H, or alkyl; R<SUP>11 </SUP>is aryl, heteroaryl, alkyl, cycloalkyl, arylalkyl, arylcycloalkyl, heteroarylalkyl, heteroarylcycloalkyl, arylheterocycloalkyl, or alkoxyalkyl. Also disclosed is a method of treating Alzheimer's Disease using one or more compounds of the invention.
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