发明名称 8-HETEROARYL XANTHINE ADENOSINE A2B RECEPTORANTAGONISTS
摘要 The present invention relates generally to compounds of formula (I): wherein X is a five or six-membered heteroaromatic ring, containing one to four heteroatoms, selected from nitrogen, oxygen, or sulfur, provided that at least one heteroatom is nitrogen; and G<SUP>1 </SUP>and G<SUP>2 </SUP>are independently CH or N. The present invention also relates to the preparation of the compounds, pharmaceutical formulations thereof, and their use in medicine as potent or selective A<SUB>2B </SUB>adenosine receptor antagonists and their uses for treating asthma, autoimmune diseases and retinal vascular diseases.
申请公布号 KR20040080939(A) 申请公布日期 2004.09.20
申请号 KR20037014277 申请日期 2003.10.31
申请人 发明人
分类号 C07D473/06;A61K31/522;A61K31/5377;A61P1/04;A61P3/10;A61P5/50;A61P9/10;A61P11/00;A61P11/02;A61P11/06;A61P17/00;A61P19/02;A61P25/00;A61P27/02;A61P29/00;A61P35/00;A61P37/02;A61P37/08;A61P43/00;C07D473/04;C07D473/08 主分类号 C07D473/06
代理机构 代理人
主权项
地址