发明名称 Process for preparation of phenethylamine derivatives
摘要 A process for the preparation of a compound of formula I, wherein R1 and R2 are ortho or para substituents, independently selected from the group consisting of hydrogen, hydroxyl, C1-C6 alkyl, C1-C6 alkoxy, C7-C9 aralkoxy, C2-C7 alkanoyloxy, C1-C6 alkylmercapto, halo and trifluoromethyl; R3 is hydrogen or C1-C6 alkyl ; R4 is hydrogen, C1-C6 alkyl, formyl or C2-C7 alkanoyl; n is one of the integers 0, 1, 2, 3 or 4; and the dotted line represents optional olefinic unsaturation; comprising hydrogenating a compound of formula III, in the presence of a nickel or cobalt catalyst at a temperature of about 5° C. to 25° C.
申请公布号 US2004181093(A1) 申请公布日期 2004.09.16
申请号 US20040797705 申请日期 2004.03.10
申请人 WYETH 发明人 KIM KEUN-SIK;KIM KWANG-IL;CHAI KI-BYUNG
分类号 C07C213/02;C07C215/42;C07C217/74;(IPC1-7):C0729/48 主分类号 C07C213/02
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