| 摘要 |
The present invention is directed to compounds of the formula (I): (wherein R<1>, R<2>, R<3>, R<4>, R<5>, R<6>, R<7>, R<8>, R<9>, R<10>, X, n and the dashed line are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2. |
| 申请人 |
MERCK & CO., INC.;MERCK SHARP & DOHME LIMITED;JIAO, RICHARD;MORRIELLO, GREGORI;YANG, LIHU;GOBLE, STEPHEN, D.;MILLS, SANDER, G.;PASTERNAK, ALEXANDER;ZHOU, CHANGYOU;BUTORA, GABOR;KOTHANDARAMAN, SHANKARAN;GUIADEEN, DEODIALSINGH;TANG, CHENG;MOYES, CHRISTOPHER |
发明人 |
JIAO, RICHARD;MORRIELLO, GREGORI;YANG, LIHU;GOBLE, STEPHEN, D.;MILLS, SANDER, G.;PASTERNAK, ALEXANDER;ZHOU, CHANGYOU;BUTORA, GABOR;KOTHANDARAMAN, SHANKARAN;GUIADEEN, DEODIALSINGH;TANG, CHENG;MOYES, CHRISTOPHER |
