ARIPIPRAZOLE ANHYDRIDE CRYSTAL, METHOD FOR PRODUCING THE SAME AND MEDICINAL PREPARATION CONTAINING THE SAME

摘要

PROBLEM TO BE SOLVED: To provide an aripiprazole anhydrous crystal scarcely converting into a hydrate and substantially lowering no eluting properties even when a pharmaceutical preparation containing the aripiprazole anhydrous crystal is preserved over a long period.

SOLUTION: This aripiprazole anhydrous crystal exhibits the same1H-NMR spectrum as that shown in, e.g. Fig. 9, the same powder X-ray diffraction spectrum as that shown in Fig. 10 and the same IR (KBr) spectrum as that shown in Fig. 11. The aripiprazole anhydrous crystal is low hygroscopic and scarcely converts into the hydrate even when preserved over a long period.

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