摘要 |
<p>The invention relates to compounds, substituted guinoline-carboxylic acids and the derivatives thereof of general formula (1, 2, 3), the pharmaceutically acceptable salts thereof, N-oxides or hydrates and methods for the production thereof, a focused library, pharmaceutical compounds and the use thereof. Said compounds are embodied in the form of Caspase enzyme inhibitors and usefully used for curing various diseases associated to an increased apoptosis activity.</p> |
申请人 |
"CHEMICAL DIVERSITY RESEARCH INSTITUTE", LTD.;IVASHCHENKO, ALEXANDER VASILIEVICH;KOBAK, VLADIMIR VASILIEVICH;KYSIL, VOLODYMYR MIKHAILOVICH;KUZOVKOVA, YULIA ALEKSANDROVNA;ILYIN, ALEXEY PETROVICH;KRAVCHENKO, DMITRI VLADIMIROVICH;TKACHENKO, SERGEY YEVGENIEVICH;KHVAT, ALEXANDER VIKTOROVICH;OKUN, ILYA MATUSOVICH |
发明人 |
IVASHCHENKO, ALEXANDER VASILIEVICH;KOBAK, VLADIMIR VASILIEVICH;KYSIL, VOLODYMYR MIKHAILOVICH;KUZOVKOVA, YULIA ALEKSANDROVNA;ILYIN, ALEXEY PETROVICH;KRAVCHENKO, DMITRI VLADIMIROVICH;TKACHENKO, SERGEY YEVGENIEVICH;KHVAT, ALEXANDER VIKTOROVICH;OKUN, ILYA MATUSOVICH |