发明名称 SELECTION OF PATIENTS WITH INCREASED RESPONSIVENESS TO BOTULINUM TOXIN
摘要 <p>Botulinum toxin has been shown to be useful for the treatment of pain when administered for cervical dystonia. Given efficacy for pain relief in regional dystonia, further expanded applications have included myofascial pain, muscle tension headache practice has expanded to migraine as well as certain secondary headache syndromes. Although multiple case reports involving the use of botulinum toxin have shown prose in it utility for the treatment of primary pain syndromes, to date, controlled trials have failed to consistently and more definitively prove utility. Described herein is a method for selection of patients with headache syndromes more likely to respond to botulinum administration. The method involves identifying coincident diseases and signs within the patient's medical history, and selecting such patients for induction into clinical studies for pain or preferential primary treatment of pain using a botulinum based pharmaceutical.</p>
申请公布号 WO2004078200(A1) 申请公布日期 2004.09.16
申请号 WO2004IB00630 申请日期 2004.03.08
申请人 BOTULINUM TOXIN RESEARCH ASSOCIATES, INC. 发明人 BORODIC, GARY, E.
分类号 A61K38/48;A61P25/00;(IPC1-7):A61K38/48 主分类号 A61K38/48
代理机构 代理人
主权项
地址