| 摘要 |
A process for the preparation of a 4-(4-flourophenyl)-6-alkyl-2-N-alkansulfonyl-N-alkylamino)pyrimidine-5-carboxylic acid ester of formula (Ib), in which R<1>, R<2>, R<3 and R><4 >are identical or different and are each a C1-6-alkyl. A 2-[-1-amino-1-(4-flourophenyl)methylene]-4-alkyl-3-oxo-alkanoicacid ester of formula (IIIb), in which R<3 >and R<4 >have the above -mentioned meanings, is reacted with an N-cyano-N-alkylalkanesulfonamide, optionally isolated or prepares in situ, formula (IVb), in which R<1 >and R<2 >have the above-mentioned meanings, to give the final product of formula (Ib).
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