发明名称 |
Transcriptional regulation of kinase inhibitors |
摘要 |
The invention relates to the transcriptional regulation of a family of proteins defined by the presence of an RKIP motif. Proteins comprising the RKIP motif modulate kinases involved in signal transduction pathways. Transcriptional regulation of proteins containing an RKIP motif forms the basis for screening assays for the identification of agents useful for modulating signal transduction pathways subject to RKIP family mediated regulation, and for the diagnosis and treatment of disorders involving inappropriate activities of pathways subject to RKIP family mediated regulation.
|
申请公布号 |
US2004180341(A1) |
申请公布日期 |
2004.09.16 |
申请号 |
US20030384435 |
申请日期 |
2003.03.07 |
申请人 |
BROWN UNIVERSITY |
发明人 |
SEDIVY JOHN M.;KOLCH WALTER;YEUNG KAM CHI |
分类号 |
A61K38/00;C12Q1/68;(IPC1-7):C12Q1/68;G01N33/574 |
主分类号 |
A61K38/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|