The present invention provides a method of diagnosing the presence or severity of liver fibrosis in an individual by detecting alpha2-macroglobulin (alpha2-MG) in sample from the individual; detecting hyaluronic acid (HA) in a sample from the individual; detecting tissue inhibitor of metalloproteinases-1 (TIMP-1) in a sample from the individual; and diagnosing the presence or severity of liver fibrosis in the individual based on the presence or level of alpha-MG, HA and TIMP-1.
申请公布号
WO03073822(A3)
申请公布日期
2004.09.16
申请号
WO2003US06038
申请日期
2003.02.28
申请人
PROMETHEUS LABORATORIES, INC.;ROSE, STEVEN, L.;OH, ESTHER, H.;WALSH, MICHAEL, J.
发明人
ROSE, STEVEN, L.;OH, ESTHER, H.;WALSH, MICHAEL, J.
