发明名称 Process for the preparation 3-aryl-2-hydroxypropionic acid derivative.
摘要 A process for the preparation of a compound of formula I in which R represents H or an acid protecting group which comprises reacting a compound of formula II in which R is as previously defined with a compound of formula III wherein X is a suitable leaving group in the presence of a base and a phase transfer catalyst at a temperature in the range 50° C. to 150° C.
申请公布号 ZA200309216(B) 申请公布日期 2004.09.16
申请号 ZA20030009216 申请日期 2003.11.26
申请人 ASTRAZENECA AB. 发明人 ROBERT EHRL;WILLIAM MACKINTOSH;PANAGIOTIS IOANNIDIS
分类号 A61K;C07B61/00;C07C;C07C303/30;C07C309/66 主分类号 A61K
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