发明名称 |
Process for the preparation 3-aryl-2-hydroxypropionic acid derivative. |
摘要 |
A process for the preparation of a compound of formula I in which R represents H or an acid protecting group which comprises reacting a compound of formula II in which R is as previously defined with a compound of formula III wherein X is a suitable leaving group in the presence of a base and a phase transfer catalyst at a temperature in the range 50° C. to 150° C. |
申请公布号 |
ZA200309216(B) |
申请公布日期 |
2004.09.16 |
申请号 |
ZA20030009216 |
申请日期 |
2003.11.26 |
申请人 |
ASTRAZENECA AB. |
发明人 |
ROBERT EHRL;WILLIAM MACKINTOSH;PANAGIOTIS IOANNIDIS |
分类号 |
A61K;C07B61/00;C07C;C07C303/30;C07C309/66 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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