PHARMACEUTICAL COMPOSITIONS CONTAINING SULPHONIC ACID DERIVATIVES

摘要

The invention relates to a derivative of naphthalenesulphonic or quinolinesulphonic acid having formula (I), wherein: A is N or a group with formula CR<8>, in which R<8> is H, OH, NR<10>R<11>, whereby R<10> and R<11 >represent, independently of each other, H or C1-C6 alkyl, or a group with formula NH-CO-R<12>, in which R<12> is C1-C6 alkyl or C6-C10 aryl; R<1> and R<2> represent, independently of each other, H or SO3R<9>, in which R<9> is H, ammonium or a cation of an alkaline or alkaline-earth metal; R<3> is H or OH; and R<4>, R<5>, R<6> and R<7 >represent, independently of each other, H, a NR<10>R<11> group or a NH-CO-R<12 >group, on the condition that (i) at least R<1> or R<2> is SO3R<9>, and (ii) at least R<4>, R<5>, R<6> or R<7> is a NR<10>R<11> group or a NH-CO-R<12 >group, or the pharmaceutically-acceptable salts thereof. Th invention also relates to a pharmaceutically-acceptable excipient.