INDOLE DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT

摘要

Compounds represented by the following general formula (I) and salts thereof: (I) wherein each symbol is as defined in the description. Because of binding and antagonizing to PGD2 receptor, the compounds represented by the general formula (I) are useful in preventing and/or treating allergic diseases (allergic rhinitis, allergic conjunctivitis, atopic dermatitis, bronchial asthma, food allergy, etc.), systemic mastocytosis, systemic mast cell activation disorder, anaphylactic shock, airway contraction, diseases accompanied by itching such as urticaria, eczema (atopic dermatitis, urticaria, etc.), diseases (cataract, retinal detachment, inflammation, infection, sleeping disorder, etc.) secondary occurring in association with behaviors caused by itching (scratching, beating, etc.), inflammation, chronic obstructive pulmonary disease, ischemic reperfusion injury, cerebrovascular disorder, autoimmune diseases, rheumatoid arthritis, pleurisy, ulcerative colitis, hypersensitive colon syndrome, etc.