发明名称 |
PYRIMIDINE DERIVATIVES AS MODULATORS OF INSULINE-LIKE GROWTH FACTOR-1 RECEPTOR (IGF-I) |
摘要 |
<p>The invention provides compounds of formula in which R1, R2, R3 and R4 have the meanings defined in the specification; processes for their preparation; pharmaceutical compositions containing them; a process for preparing the pharmaceutical compositions; and their use in therapy.</p> |
申请公布号 |
EP1456182(A1) |
申请公布日期 |
2004.09.15 |
申请号 |
EP20020791165 |
申请日期 |
2002.12.03 |
申请人 |
ASTRAZENECA AB |
发明人 |
BARLAAM, BERNARD;PAPE, ANDREW;THOMAS, ANDREW |
分类号 |
A61K31/505;A61K31/506;A61P35/00;A61P43/00;C07D239/48;C07D401/14;C07D403/12;C07D403/14;C07D405/14;C07D409/14;C07D413/14;(IPC1-7):C07D239/48 |
主分类号 |
A61K31/505 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|