| 摘要 |
Injectable formulation for diagnostics or photodynamic therapy contains up to 10 mg/ml alkali metal salt of an organopalladium complex (I) in aqueous carrier containing benzyl alcohol-ethanol mixture (ratio 15:85-25:75) or propylene glycol as photosensitizer solubilizing agent and up to 20 wt.% of a surfactant to decrease the aggregation of the photosensitizer. An injectable formulation for diagnostics or photodynamic therapy contains up to 10 mg/ml of an alkali metal salt of an organopalladium complex of formula (I) in an aqueous carrier containing a benzyl alcohol -ethanol mixture in the ratio 15:85-25:75 or propylene glycol as photosensitizer solubilizing agent and up to 20 wt.% (calculated on the weight of the final formulation) of a surfactant to decrease the aggregation of the photosensitizer. R2 = H, OH or COOR4; R3 = H, OH, or 1-12C alkyl; and R4 = H, 1-12C alkyl, or 3-12C cycloalkyl. |
