COVALENT MODIFICATION OF RNA FOR IN VITRO AND IN VIVO DELIVERY
摘要
<p>The post-synthetic modification of RNA for the delivery of the RNA to a mammalian cell is described. The modifications enhance resistant of the RNA to nuclease digestion and delivery of the RNA to the cell whether the RNA is delivered alone or in combination with a transfection agent. Activity of the RNA in the cell is maintained.</p>
申请公布号
WO2004076630(A2)
申请公布日期
2004.09.10
申请号
WO2004US05096
申请日期
2004.02.20
申请人
MIRUS CORPORATION
发明人
MONAHAN, SEAN, D.;BUDKER, VLADIMIR, G.;NADER, LISA;SUBBOTIN, VLADIMIR;WOLFF, JON, A.