NOVEL SOLID BODY FORMS OF MESOPROGESTIN 11B-[4E-(HYDROXYIMINOMETHYL) -PHENYL]-17A -METHOXYMETHYL -17B-METHOXY -ESTRA-4, 9-DIEN-3 -ONE.

摘要

The invention relates to novel solid body forms of mesoprogestin 11-[4E -(hydroxyiminomethyl)-phenyl] -17a-methoxymethyl -17b-methoxy-estra-4, 9-dien-3 -one (oxime J 867), particularly a highly pure and stable amorphous or highly crystalline form (ansolvate/anhydrate) of compound J 867. The invention also relates to methods for producing said novel solid body forms and to the use thereof in pharmaceutical compositions. The novel solid body forms are characterized by exhibiting a high degree of stability. The solid body forms of oxime J 867 can, in particular, be used in the area of fertility control and in hormone replacement therapy.