Conjugates of a Factor VIII moiety and one or more water-soluble polymers are provided. Typically, the water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided are compositions comprising the conjugates, methods of making the conjugates, and methods of administering compositions comprising the conjugates to a patient.
申请公布号
WO2004075923(A2)
申请公布日期
2004.09.10
申请号
WO2004US06034
申请日期
2004.02.26
申请人
NEKTAR THERAPEUTICS AL, CORPORATION;BOSSARD, MARY, J.;BENTLEY, MICHAEL, D.