NOVEL PROCESS FOR THE PREPARATION OF agr;(24DISULFOPHENYL)NTERTBUTYLNITRONE AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF.

摘要

An integrated process for preparing agr;(2, 4disulfophenyl)Ntertbutylnitrone and its salts is disclosed in whichNtertbutylhydroxylamine acid addition salt is incompletely neutralised so as to leave catalytic amounts of acid and the neutralisation product is condensed with an appropriate aldehyde.