IMMUNOTHERAPEUTIC COMBINATIONS FOR THE TREATMENT OF TUMORS.

摘要

The invention relates to the field of immunology, more specifically to cancer immunotherapy, especially using immunotherapeutic combinations and treatment methods to prevent the growth of tumor cell and/or eliminate said cells. The methods disclosed in the invention are based on the blockage of kinase protein receptors in tyrosine residues (RTK) and the ligands for said receptors. The invention describes immunotherapeutic combinations which block the RTK receptors and/or their ligands by combining active and/or passive immunotherapy against said receptors. The methods disclosed can be used in patients with different clinical states of tumors of epithelial origin which overexpress said receptors. The active and passive immunotherapeutic combination can be used simultaneously or sequentially depending on whether the therapeutic method is being used in patients with an advanced disease state or as adjuvant therapy.