NUCLEOTIDE AND AMINO ACID SEQUENCES OF OOCYTE FACTORS FOR ALTERING OVARIAN FOLLICULAR GROWTH IN VIVO OR IN VITRO.

摘要

The present invention relates to nucleotide and amino acid sequences of oocyte factors for altering ovarian follicular growth in vivo or in vitro. The present invention also concerns novel homodimeric and heterodimeric polypeptides and their use for altering mammalian ovarian follicular growth in vivo or in vitro. In particular, the invention broadly concerns active or passive immunisation against these homo- or heterodimeric polypeptides or functional fragments or variants thereof so as to alter follicular growth in vivo or in vitro.