发明名称 |
Crohn's disease antibody-binding peptide and method of examining crohn's disease |
摘要 |
The invention provides that examination reagents useful in diagnosing Crohn's disease and a method of conveniently and accurately detecting the occurrence of Crohn's disease. The examination reagents contain as the active ingredient a Crohn's disease antibody-binding protein as defined in the following (a) or (b): (a) a peptide consisting of an amino acid sequence selected from among the amino acid sequences represented by SEQ ID NOS:1 to 4; and (b) a peptide consisting of an amino acid sequence derived from the above-mentioned amino acid sequence (a) by substitution, deletion or addition of one to several amino acids and being capable of binding to the Crohn's disease antibody. The examination method can be carried out by detecting the presence/absence of an antibody recognizing human vacuolar H<+>-transport ATPase, a human nuclear protein (Homo sapiens kruppel-like zinc finger protein 300) or rice allergen in a biological sample of a subject.
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申请公布号 |
US2004175763(A1) |
申请公布日期 |
2004.09.09 |
申请号 |
US20030475647 |
申请日期 |
2003.10.23 |
申请人 |
SAITO HIROSHI;KATSURAGAI KIYONORI;TACHIKAWA TETSUYA;TANAKA MICHINORI;OGINO KOICHI;TAKI TAKAO |
发明人 |
SAITO HIROSHI;KATSURAGAI KIYONORI;TACHIKAWA TETSUYA;TANAKA MICHINORI;OGINO KOICHI;TAKI TAKAO |
分类号 |
C07K14/415;C07K14/47;G01N33/564;(IPC1-7):A61K39/395;G01N33/53;G01N33/567;C07K16/42 |
主分类号 |
C07K14/415 |
代理机构 |
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地址 |
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