发明名称 Substituted nitrogen-containing heterobicycles, the preparation thereof and their use as pharmaceutical compositions
摘要 The present invention relates to new substituted nitrogen-containing heterobicyclic compounds of general formula wherein B, X<1 >to X<3 >and R<1 >to R<5 >are defined as in claim 1, the tautomers, the enantiomers, the diastereomers, the mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, which have valuable properties. The compounds of the above general formula I as well as the tautomers, the enantiomers, the diastereomers, the mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, and their stereoisomers have valuable pharmacological properties, particularly an antithrombotic activity and a factor Xa-inhibiting activity.
申请公布号 US2004176603(A1) 申请公布日期 2004.09.09
申请号 US20030739172 申请日期 2003.12.18
申请人 BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG 发明人 PRIEPKE HENNING;PFAU ROLAND;GERLACH KAI;RIES UWE;WIENEN WOLFGANG;BAUER ECKHART;NAR HERBERT
分类号 C07D401/12;C07D401/14;C07D403/12;C07D403/14;C07D405/14;C07D409/12;C07D409/14;C07D417/12;C07D417/14;C07D471/04;C07D487/04;C07D495/04;C07D498/10;(IPC1-7):C07D217/22;C07D215/38;C07D237/26 主分类号 C07D401/12
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