Electrochemical device for detecting ligand-binding reactions, useful e.g. for diagnosis and toxicological testing, includes measuring chamber where ligands and sample are applied to a biochip that carries binding agents

摘要

A device for electrochemical detection of ligate-ligand association events, particularly for performing displacement assays as described in the process claims of , is new. Device for electrochemical detection of ligate-ligand association events, particularly for performing displacement assays as described in the process claims of comprises: (a) measuring chamber (310) for holding a substrate (200), the surface of which is modified by application of at least one sort of ligate (I); (b) system for supplying signal ligands (II) and a sample to the surface of (200); (c) device (X) that detects (II) by a surface-sensitive, electrochemical detection method; and (d) a unit for comparing the values determined by (X) with reference values.