发明名称 |
Infectious flavivirus pseudo-particles containing functional prM-E envelope proteins |
摘要 |
The invention relates to the generation and the use of flavivirus pseudo-particles containing native functional prM and E envelope glycoproteins assembled onto retroviral core particles. These particles are highly infectious and constitute a valid model of flavivirus virion whose handling does not require category 3 or 4 laboratories.
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申请公布号 |
EP1454988(A1) |
申请公布日期 |
2004.09.08 |
申请号 |
EP20030290504 |
申请日期 |
2003.03.03 |
申请人 |
INSTITUT NATIONAL DE LA SANTE ETDE LA RECHERCHE MEDICALE (INSERM) |
发明人 |
BARTOSCH, BIRKE;COSSET, FRANCOIS-LOIC |
分类号 |
A61K39/12;A61K48/00;C07K14/18;C12N7/04;C12N15/40;C12N15/86;C12N15/867;G01N33/569;(IPC1-7):C12N15/86 |
主分类号 |
A61K39/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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