发明名称 2-amino-4,5 heptenoic acid derivatives useful as nitric oxide synthase inhibitors
摘要 The present invention is directed to a compound of formula I:or a pharmaceutically acceptable salt thereof, wherein:R1 is selected from the group consisting of H and methyl; andR2 is selected from the group consisting of H and methyl.The compounds possess useful nitric oxide synthetase inhibiting activity, and are expected to be useful in the treatment or prophylaxis of a disease or condition in which the synthesis or over synthesis of nitric oxide forms a contributory part.
申请公布号 US6787668(B2) 申请公布日期 2004.09.07
申请号 US20010835196 申请日期 2001.04.13
申请人 PHARMACIA CORPORATION 发明人 PITZELE BARNETT S.;SIKORSKI JAMES A.;WEBBER RONALD KEITH
分类号 C07C257/14;(IPC1-7):C07C257/00 主分类号 C07C257/14
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