发明名称 |
2-amino-4,5 heptenoic acid derivatives useful as nitric oxide synthase inhibitors |
摘要 |
The present invention is directed to a compound of formula I:or a pharmaceutically acceptable salt thereof, wherein:R1 is selected from the group consisting of H and methyl; andR2 is selected from the group consisting of H and methyl.The compounds possess useful nitric oxide synthetase inhibiting activity, and are expected to be useful in the treatment or prophylaxis of a disease or condition in which the synthesis or over synthesis of nitric oxide forms a contributory part.
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申请公布号 |
US6787668(B2) |
申请公布日期 |
2004.09.07 |
申请号 |
US20010835196 |
申请日期 |
2001.04.13 |
申请人 |
PHARMACIA CORPORATION |
发明人 |
PITZELE BARNETT S.;SIKORSKI JAMES A.;WEBBER RONALD KEITH |
分类号 |
C07C257/14;(IPC1-7):C07C257/00 |
主分类号 |
C07C257/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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