| 发明名称 |
N,N'-substituted-1,3-diamino-2-hydroxypropane derivatives |
| 摘要 |
Disclosed are compounds of the formula wherein the variables RN, RC, R1, R25, R2, and R3 are as defined herein. These compounds have activity as inhibitors of beta-secretase and are therefore useful in treating a variety of discorders such as Alzheimer's Disease.
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| 申请公布号 |
US2004171881(A1) |
申请公布日期 |
2004.09.02 |
| 申请号 |
US20020291318 |
申请日期 |
2002.11.08 |
| 申请人 |
JOHN VARGHESE;MAILLARD MICHEL;JAGODZINSKA BARBARA;BECK JAMES;GAILUNAS ANDREA;FRESKOS JOHN;MICKELSON JOHN;SAMALA LAKSHMAN;SEALY JENNIFER;TENBRINK RUTH;FANG LAWRENCE;HOM ROY |
发明人 |
JOHN VARGHESE;MAILLARD MICHEL;JAGODZINSKA BARBARA;BECK JAMES;GAILUNAS ANDREA;FRESKOS JOHN;MICKELSON JOHN;SAMALA LAKSHMAN;SEALY JENNIFER;TENBRINK RUTH;FANG LAWRENCE;HOM ROY |
| 分类号 |
C07D295/16;A61K31/164;A61K31/18;A61K31/27;A61K31/336;A61K31/341;A61K31/357;A61K31/36;A61K31/381;A61K31/39;A61K31/40;A61K31/41;A61K31/415;A61K31/416;A61K31/4164;A61K31/421;A61K31/423;A61K31/426;A61K31/427;A61K31/428;A61K31/437;A61K31/439;A61K31/4402;A61K31/4409;A61K31/4418;A61K31/4439;A61K31/445;A61K31/455;A61K31/47;A61K31/495;A61P25/28;A61P43/00;C07C217/58;C07C233/36;C07C233/40;C07C233/58;C07C233/78;C07C235/20;C07C235/50;C07C235/74;C07C237/04;C07C237/06;C07C237/08;C07C237/22;C07C237/42;C07C251/38;C07C255/58;C07C271/28;C07C271/44;C07C311/08;C07C311/16;C07C311/17;C07C311/18;C07C311/19;C07C311/20;C07C311/21;C07C311/29;C07C311/37;C07C317/44;C07C317/46;C07C317/50;C07C323/60;C07C323/62;C07C323/65;C07D;C07D207/06;C07D207/08;C07D207/14;C07D207/26;C07D207/267;C07D207/27;C07D207/48;C07D209/08;C07D209/42;C07D211/10;C07D211/44;C07D211/58;C07D211/60;C07D211/96;C07D213/36;C07D213/56;C07D213/64;C07D213/71;C07D213/80;C07D213/81;C07D213/82;C07D213/85;C07D213/89;C07D215/36;C07D215/42;C07D215/48;C07D215/54;C07D215/56;C07D217/08;C07D217/22;C07D223/10;C07D231/14;C07D231/38;C07D231/56;C07D233/64;C07D233/84;C07D233/90;C07D237/14;C07D239/28;C07D239/34;C07D239/42;C07D239/48;C07D241/08;C07D241/20;C07D241/24;C07D241/44;C07D243/08;C07D249/06;C07D249/10;C07D251/46;C07D251/54;C07D257/04;C07D257/06;C07D261/08;C07D261/14;C07D261/18;C07D263/06;C07D263/32;C07D263/34;C07D263/48;C07D263/54;C07D263/56;C07D263/58;C07D265/36;C07D271/06;C07D271/08;C07D271/12;C07D275/06;C07D277/20;C07D277/30;C07D277/36;C07D277/56;C07D277/68;C07D277/82;C07D279/08;C07D279/16;C07D285/06;C07D285/10;C07D285/12;C07D285/135;C07D295/155;C07D295/185;C07D295/192;C07D295/22;C07D295/26;C07D303/36;C07D307/20;C07D307/46;C07D307/52;C07D307/68;C07D307/84;C07D307/86;C07D307/91;C07D309/12;C07D311/04;C07D311/58;C07D317/68;C07D319/18;C07D327/06;C07D333/20;C07D333/22;C07D333/32;C07D333/34;C07D333/38;C07D333/58;C07D333/62;C07D333/68;C07D333/72;C07D335/06;C07D401/04;C07D403/04;C07D405/12;C07D409/04;C07D411/12;C07D413/04;C07D413/06;C07D413/12;C07D417/04;C07D417/12;C07D453/02;C07D471/04;C07D473/06;C07D473/08;C07D473/16;C07D487/04;C07D495/04;C07D498/04;(IPC1-7):C07C255/53;C07C215/46 |
主分类号 |
C07D295/16 |
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